Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gly71Arg UGT1A1 polymorphism is associated with breast cancer susceptibility in Han Chinese women.

Genetics and molecular research : GMR - 12 Aug 2016

Shi J, Li L H, Duan X Y, Liu Q, Sun L L, Tian Y T

Abstract excerpt

Breast cancer is among the most common causes of cancer-related death in women worldwide. Previous studies have demonstrated an association between prolonged estrogen exposure and increased risk of breast cancer. Uridine 5'-diphospho-glucuronosyltransferase 1-1 (UGT1A1) plays a significant role in the detoxification of estrogens. Two major genetic polymorphisms have been identified in the UGT1A1 locus. UGT1A1*28...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Asian People
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gastrointestinal Neoplasms

Share to Gene Frequency

Share to Genetic Association Studies

Share to Glucuronosyltransferase

Source

Identifiers

PMID: 27525948
DOI: 10.4238/gmr.15038332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gly71Arg UGT1A1 polymorphism is associated with breast cancer susceptibility in Han Chinese women.PMID 27525948Read ↗

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 (UGT1A1) and risk of breast cancer.Semantic proximity Read ↗

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans.Semantic proximity Read ↗

[Association of polymorphisms in SULT1A1 and UGT1A1 Genes with breast cancer risk and phenotypes in Russian women].Semantic proximity Read ↗

Association between UDP-glucuronosyltransferase 2B7 tagSNPs and breast cancer risk in Chinese females.Semantic proximity Read ↗

Genetic polymorphisms in the UGT1A1 gene and breast cancer risk in Greek women.Semantic proximity Read ↗

The association between TA-repeat polymorphism in the promoter region of UGT1A1 and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Semantic proximity Read ↗

Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review.Semantic proximity Read ↗

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans.Semantic proximity Read ↗

CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case-control study.Semantic proximity Read ↗

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.Semantic proximity Read ↗

Cytochrome P450 1A1 (CYP1A1) Gene Polymorphisms and Susceptibility to Breast Cancer: a Meta-Analysis in the Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.