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Article

Genetic polymorphisms in the UGT1A1 gene and breast cancer risk in Greek women.

Genetic testing - 1 Jan 2007

Tsezou Aspasia, Tzetis Maria, Giannatou Eirini, Gennatas Constantinos, Pampanos Andreas, Kanavakis Emmanuel, Kitsiou-Tzeli Sofia

Abstract excerpt

Uridine diphospho-glucuronosyltransferase 1 (UGT1A1) is involved in estradiol glucuronidation, which may play a central role in the etiology of breast cancer. A common insertion/deletion polymorphism in the TATAA-box of the promoter region of UGT1A1 results in decreased initiation of transcription, and has been associated with breast cancer risk in different ethnic groups. In the present study, the role of the...

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Identifiers

PMID: 17949292
DOI: 10.1089/gte.2007.0020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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