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Article

Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.

Cell reports - 23 Aug 2016

Niwa Shinsuke, Lipton David M, Morikawa Manatsu, Zhao Charles, Hirokawa Nobutaka, Lu Hang, Shen Kang

Abstract excerpt

Kinesin motor proteins transport intracellular cargoes throughout cells by hydrolyzing ATP and moving along microtubule tracks. Intramolecular autoinhibitory interactions have been shown for several kinesins in vitro; however, the physiological significance of autoinhibition remains poorly understood. Here, we identified four mutations in the stalk region and motor domain of the synaptic vesicle (SV) kinesin...

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Identifiers

PMID: 27524618
DOI: 10.1016/j.celrep.2016.07.043
PMCID: PMC5432123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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