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Article

Lens transcriptome profile during cataract development in Mip-null mice.

Biochemical and biophysical research communications - 16 Sept 2016

Bennett Thomas M, Zhou Yuefang, Shiels Alan

Abstract excerpt

Major intrinsic protein or aquaporin-0 (MIP/AQP0) functions as a water channel and a cell-junction molecule in the vertebrate eye lens. Loss of MIP function in the lens leads to degraded optical quality and cataract formation by pathogenic mechanisms that are unclear. Here we have used microarray-hybridization analysis to detect lens transcriptome changes during cataract formation in mice that are functionally...

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Source

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Identifiers

PMID: 27524245
DOI: 10.1016/j.bbrc.2016.08.068
PMCID: PMC5002386

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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