Article
Identification of differentially expressed genes in mouse Pax6 heterozygous lenses.
Investigative ophthalmology & visual science - 1 Jun 2002
Chauhan Bharesh K, Zhang Weiyan, Cveklova Kveta, Kantorow Marc, Cvekl Ales
Abstract excerpt
PURPOSE: Pax6 is a critical regulator of the developing lens, other ocular tissues, central nervous system, and pancreas. Downstream targets of Pax6 are largely unknown. The present study was designed to identify differentially expressed genes in Pax6 heterozygous and normal mouse lenses. METHODS: RNAs from 8-week-old normal and Pax6 heterozygous mouse lenses were analyzed by both RT-PCR differential display and...
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