Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aneuploidy and asynchronous replication in non-alcholic fatty liver disease and cryptogenic cirrhosis.

Gene - 15 Nov 2016

Laish Ido, Mannasse-Green Batya, Hadary Ruth, Konikoff Fred M, Amiel Aliza, Kitay-Cohen Yona

Abstract excerpt

BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) and cryptogenic cirrhosis (CC), which is largely a late sequela of NAFLD, are considered pre-neoplastic conditions that might progress to hepatocellular carcinoma. Aneuploidy, telomere aggregates and synchronization of replication were evaluated as markers of genetic instability in these patients. METHODOLOGY: Peripheral blood lymphocytes from 22 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Cell Cycle
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Cirrhosis

Share to Lymphocytes

Share to Non-alcoholic Fatty Liver Disease

Share to Telomere

Share to Telomere Homeostasis

Source

Identifiers

PMID: 27520584
DOI: 10.1016/j.gene.2016.08.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aneuploidy and asynchronous replication in non-alcholic fatty liver disease and cryptogenic cirrhosis.PMID 27520584Read ↗

Telomere Dysfunction in Nonalcoholic Fatty Liver Disease and Cryptogenic CirrhosisSemantic proximity Read ↗

Polyploidization of Hepatocytes: Insights into the Pathogenesis of Liver DiseasesSemantic proximity Read ↗

Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver diseaseSemantic proximity Read ↗

Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLDSemantic proximity Read ↗

Frequent aneuploidy among normal human hepatocytes.Semantic proximity Read ↗

Hepatocytes Polyploidization and Cell Cycle Control in Liver PhysiopathologySemantic proximity Read ↗

Induction of autophagy promotes the growth of early preneoplastic rat liver nodulesSemantic proximity Read ↗

Changes to hepatocyte ploidy and binuclearity profiles during human chronic viral hepatitisSemantic proximity Read ↗

Single-Cell Analysis of Ploidy and Centrosomes Underscores the Peculiarity of Normal HepatocytesSemantic proximity Read ↗

Modified allelic replication in lymphocytes of patients with neurofibromatosis type 1.Semantic proximity Read ↗

Telomere Shortening Correlates With Increasing Aneuploidy of Chromosome 8 in Human Hepatocellular Carcinoma *Semantic proximity Read ↗

Liver Cell Polyploidization: A Pivotal Role for Binuclear HepatocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.