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Article

Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLD

31 Oct 2005

Abstract excerpt

AIMS: The risk factors associated with poor prognosis of nonalcoholic fatty liver disease (NAFLD) are not fully understood. Our aim was to assess the role of progressive hepatocellular telomere shortening in the clinical course of NAFLD. METHODS: We measured average telomere lengths in liver tissue samples from 44 patients with NAFLD by quantitative fluorescence in situ hybridization using a telomere-specific...

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Share to Liver Disease Diagnosis and Treatment
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PMID: 16420506
DOI: 10.1111/j.1478-3231.2005.01178.x

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