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Article

Effects of different omeprazole dosing on gastric pH in non-variceal upper gastrointestinal bleeding: A randomized prospective study.

Journal of digestive diseases - 1 Sept 2016

Chwiesko Adam, Charkiewicz Radoslaw, Niklinski Jacek, Luczaj Wojciech, Skrzydlewska Elzbieta, Milewski Robert, Baniukiewicz Andrzej, Wroblewski Eugeniusz, Rosolowski Mariusz, Dabrowski Andrzej

Abstract excerpt

OBJECTIVE: We aimed to identify the best method of omeprazole (OME) application with respect to intragastric pH, cytochrome P450 2C19 (CYP2C19) genotype and phenotype. METHODS: The patients with non-variceal upper gastrointestinal bleeding (NVUGIB) were prospectively enrolled. After the achievement of endoscopic hemostasis, the patients were randomized to 40-mg intravenous (i.v.) OME bolus injection every 12 h or...

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PMID: 27518195
DOI: 10.1111/1751-2980.12393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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