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Article

Initial 48-hour acid inhibition by intravenous infusion of omeprazole, famotidine, or both in relation to cytochrome P450 2C19 genotype status.

Clinical pharmacology and therapeutics - 1 Nov 2006

Sugimoto Mitsushige, Furuta Takahisa, Shirai Naohito, Ikuma Mutsuhiro, Hishida Akira, Ishizaki Takashi

Abstract excerpt

BACKGROUNDS AND AIMS: Faster and stronger acid inhibition is required for the treatment of hemorrhage from peptic ulcers. We compared the effects of intravenous infusion regimens of a proton pump inhibitor (PPI) alone, a histamine 2 receptor antagonist (H2RA) alone, and the combination of a PPI with an H2RA on acid inhibition in the early postadministration phase in relation to cytochrome P450 (CYP) 2C19 genotype...

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Identifiers

PMID: 17112810
DOI: 10.1016/j.clpt.2006.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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