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Article

Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo.

PLoS genetics - 1 Aug 2016

Rijal Keshab, Maraia Richard J

Abstract excerpt

The ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation is critical for abundant tRNA production during cellular proliferation, development and cancer. Yet understanding of the unique termination mechanisms used by RNAP III is incomplete, as is its link to high transcription output. We used two tRNA-mediated suppression systems to screen for Rpc1 mutants with gain- and...

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Identifiers

PMID: 27518095
DOI: 10.1371/journal.pgen.1006253
PMCID: PMC4982682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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