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Article

The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer

10 Aug 2016

Abstract excerpt

Metformin, a drug approved for diabetes type II treatment, has been associated with a reduction in the incidence of breast cancer and metastasis and increased survival in diabetic breast cancer patients. High levels of miR-26a expression have been proposed as one of the possible mechanisms for this effect; likewise, this miRNA has also been associated with survival/apoptosis processes in breast cancer. Our aim...

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PMID: 27517917
DOI: 10.3390/ijms17081298

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