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Article

MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer

8 Nov 2011

Abstract excerpt

MicroRNAs (miRNAs) are emerging as a class of small regulatory RNAs whose alterations are implicated in the initiation and progression of human cancers. Our study showed that miR-25 was highly expressed both in clinical ovarian cancer samples and cell lines. Down-regulation of miR-25 in ovarian cancer cells induced apoptosis whereas overexpression of miR-25 enhanced cell proliferation. The effects of miR-25...

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PMID: 22076535
DOI: 10.3892/or.2011.1530

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