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In-Depth Assessment of Within-Individual and Inter-Individual Variation in the B Cell Receptor Repertoire

12 Oct 2015

Abstract excerpt

High-throughput sequencing of the B cell receptor (BCR) repertoire can provide rapid characterization of the B cell response in a wide variety of applications in health, after vaccination and in infectious, inflammatory and immune-driven disease, and is starting to yield clinical applications. However, the interpretation of repertoire data is compromised by a lack of studies to assess the intra and...

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PMID: 26528292
DOI: 10.3389/fimmu.2015.00531

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