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Article

Associations between microRNA binding site SNPs in FGFs and FGFRs and the risk of non-syndromic orofacial cleft.

Scientific reports - 11 Aug 2016

Li Dandan, Zhang Hongchuang, Ma Lan, Han Yue, Xu Min, Wang Zhendong, Jiang Hongbing, Zhang Weibing, Wang Lin, Pan Yongchu

Abstract excerpt

We hypothesized that microRNA binding site single nucleotide polymorphisms (SNPs) in fibroblast growth factors (FGFs) and their receptor genes (FGFRs) may affect microRNA and mRNA interactions and are thereby associated with susceptibility of non-syndromic orofacial cleft (NSOC). Ten SNPs among the FGF and FGFR genes were selected and their associations with NSOC susceptibility were investigated in a case-control...

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Source

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Identifiers

PMID: 27511275
DOI: 10.1038/srep31054
PMCID: PMC4980626

Genes

FGF2
FGF5
FGF9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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