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Article

Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes.

Journal of human genetics - 1 Apr 2024

Sun Jialin, Li Mujia, Sun Huaqin, Lin Ziyuan, Shi Bing, Jia Zhonglin

Abstract excerpt

BACKGROUND: Non-syndromic orofacial cleft (NSOC) is one of the most common craniofacial malformations with complex etiology. This study aimed to explore the role of specific SNPs in ZFP36L2 and its functional relevance in zebrafish models. METHODS: We analyzed genetic data of the Chinese Han population from two previous GWAS, comprising of 2512 cases and 2255 controls. Based on the Hardy-Weinberg Equilibrium...

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Source

Identifiers

PMID: 38321215
DOI: 10.1038/s10038-024-01222-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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