Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The functional variant of NTN1 contributes to the risk of nonsyndromic cleft lip with or without cleft palate.

European journal of human genetics : EJHG - 1 Apr 2020

Li Dandan, Zhu Guirong, Lou Shu, Ma Lan, Zhang Chi, Pan Yongchu, Wang Lin

Abstract excerpt

Previous genome-wide association study of nonsyndromic cleft lip with or without cleft palate (NSCL/P) identified a susceptible variant (rs4791774). We hypothesized that the functional single nucleotide polymorphism (SNP) may be in linkage disequilibrium with this lead SNP. The potential functional SNP (rs4791331) was identified by bioinformatic analysis. A case-control study with 891 orofacial cleft cases and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Development

Share to Cell Cycle

Share to Cleft Lip

Share to Cleft Palate

Share to Enhancer Elements, Genetic

Share to HEK293 Cells

Share to Netrin-1

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 31780810
DOI: 10.1038/s41431-019-0549-4
PMCID: PMC7080719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The functional variant of NTN1 contributes to the risk of nonsyndromic cleft lip with or without cleft palate.PMID 31780810Read ↗

Identification of putative regulatory single-nucleotide variants in NTN1 gene associated with NSCL/P.Semantic proximity Read ↗

Exploration of Genetic Variants of Non-syndromic Cleft Lip with or without Palate and Underlying Mechanisms.Semantic proximity Read ↗

Identification of susceptibility genes in non-syndromic cleft lip with or without cleft palate using whole-exome sequencing.Semantic proximity Read ↗

Identification of Novel Genomic Variations in Susceptibility to Nonsyndromic Cleft Lip and Palate PatientsSemantic proximity Read ↗

[Exploring the association between de novo mutations and non-syndromic cleft lip with or without palate based on whole exome sequencing of case-parent trios].Semantic proximity Read ↗

Association between PAX7 and NTN1 gene polymorphisms and nonsyndromic orofacial clefts in a northern Chinese population.Semantic proximity Read ↗

[Progress in next-generation sequencing research of non-syndromic oral clefts].Semantic proximity Read ↗

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Using whole exome sequencing to identify susceptibility genes associated with nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Association of EPHA3 Gene Polymorphisms with Nonsyndromic Cleft Lip With or Without Cleft Palate.Semantic proximity Read ↗

Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.Semantic proximity Read ↗

Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.