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Article

Establishment and gene expression analysis of disease-derived induced pluripotent stem cells of scleroderma.

Journal of dermatological science - 1 Nov 2016

Wang Zhongzhi, Nakamura Kayo, Jinnin Masatoshi, Kudo Hideo, Goto Mizuki, Era Takumi, Kira Tomomi, Nakashima Taiji, Fukushima Satoshi, Ihn Hironobu

Abstract excerpt

BACKGROUND: We recently generated induced pluripotent stem cells (iPSCs) from cultured dermal fibroblasts of systemic sclerosis (SSc-iPSC) to study the disease mechanisms. OBJECTIVE: In the present study, we have performed gene expression analysis using cultured SSc dermal fibroblasts, SSc-iPSC, and fibroblasts re-differentiated from SSc-iPSC (SSc-iPSC-FB). METHODS: mRNA and protein levels of collagen and...

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Source

Identifiers

PMID: 27510999
DOI: 10.1016/j.jdermsci.2016.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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