Article

Comparative Transcriptomic Analysis Validates iPSC Derived In-Vitro Progressive Fibrosis Model As A Screening Tool For Drug Discovery and Development in SSc

2024-07-01

Abstract excerpt

<title>Abstract</title> <p>Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune dysregulation, and systemic fibrosis. Research on SSc has been hindered largely by lack of relevant models to study the progressive nature of the disease and to recapitulate the cell plasticity that is observed in this disease context. Generation of models for fibrotic disease using pluripotent stem...

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Literature Corpus work: fa392edb-8073-536d-b641-dc47051e7ea5
DOI: 10.21203/rs.3.rs-4546782/v1

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