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Article

Expression and Pathogenic Analysis of Integrin Family Genes in Systemic Sclerosis

20 Jul 2021

Abstract excerpt

Objectives: Emerging evidence shows that integrin members are involved in inflammation and fibrosis in systemic sclerosis (SSc). This study aimed at evaluating the expression of integrin family genes in the skin tissue from SSc patients and exploring the potential pathogenic mechanism. Methods: We utilized the public datasets of SSc skin tissue from the Gene Expression Omnibus (GEO) database to analyze the...

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PMID: 34355002
DOI: 10.3389/fmed.2021.674523

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