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Article

Predisposition of an Intronic Duplication in CHEK2 Gene in the Cases of Breast Cancer from Balochistan.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2025

Baloch Abdul Hameed, Shuja Jamila, Bangulzai Nasrullah, Jan Mohammad, Sattar Abdul, Brohi Sarfaraz Ahmed, Habibullah Habibullah, Baloch Dost Muhammad, Ahmad Jamil

Abstract excerpt

OBJECTIVE: After BRCA 1&2, CHEK2 is the most frequently predisposing altered gene causing breast cancer in female. The prime objective of the current study was to analyze germline CHEK2 variants and their association with breast cancer in Balochistani population. METHODS: Breast cancer is among the most prevalent cancers worldwide and most common diagnosed cancer in women. Mutations in many proto-oncogenes and...

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Source

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Identifiers

PMID: 41312922
DOI: 10.31557/APJCP.2025.26.11.3975
PMCID: PMC12927507

Genes

CHEK2
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Predisposition of an Intronic Duplication in CHEK2 Gene in the Cases of Breast Cancer from Balochistan.PMID 41312922Read ↗

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