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Article

EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma.

Scientific reports - 9 Aug 2016

Han Chuangye, Liao Xiwen, Qin Wei, Yu Long, Liu Xiaoguang, Chen Gang, Liu Zhengtao, Lu Sicong, Chen Zhiwei, Su Hao, Zhu Guangzhi, Lu Zili, Liu Zhiming, Qin Xue, Gui Ying, Mo Zengnan, Li Lequn, Peng Tao

Abstract excerpt

This study was to explore the association between gene variants and p21 expression and investigate the TP53-independent p21 regulation in hepatitis B virus (HBV) related hepatocellular carcinoma (HCC) patients from Guangxi by genome-wide association study. 426 HBV-related HCC patients were enrolled. Results showed that, after quality control, a total of 21,643 SNPs were identified in 107 p21 positive and 298 p21...

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Share to Carcinoma, Hepatocellular
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27502069
DOI: 10.1038/srep31237
PMCID: PMC4977508

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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