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Article

Genetic and clinical characteristics of Japanese patients with sporadic somatotropinoma.

Endocrine journal - 30 Nov 2016

Matsumoto Ryusaku, Izawa Masako, Fukuoka Hidenori, Iguchi Genzo, Odake Yukiko, Yoshida Kenichi, Bando Hironori, Suda Kentaro, Nishizawa Hitoshi, Takahashi Michiko, Inoshita Naoko, Yamada Shozo, Ogawa Wataru, Takahashi Yutaka

Abstract excerpt

Most of acromegaly is caused by a sporadic somatotropinoma and a couple of novel gene mutations responsible for somatotropinoma have recently been reported. To determine the cause of sporadic somatotropinoma in Japanese patients, we analyzed 61 consecutive Japanese patients with somatotropinoma without apparent family history. Comprehensive genetic analysis revealed that 31 patients harbored guanine...

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Source

Identifiers

PMID: 27498687
DOI: 10.1507/endocrj.EJ16-0075

Genes

AIP
GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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