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Article

Germline mutations of AIP gene in somatotropinomas resistant to somatostatin analogues

4 Oct 2012

Abstract excerpt

OBJECTIVE: Most cases of familial isolated pituitary adenomas with mutated aryl hydrocarbon receptor-interacting protein (AIP:HGNC:358) gene develop somatotropinomas. They are characterised by an aggressive clinical phenotype including early age at diagnosis, large tumours and frequent invasiveness. There is little information on AIP gene mutations' prevalence in isolated somatotropinomas characterised by poor...

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Share to Adrenal and Paraganglionic Tumors
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PMID: 23038625
DOI: 10.1530/eje-12-0457

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Germline mutations of AIP gene in somatotropinomas resistant to somatostatin analoguesPMID 23038625Read ↗

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