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Article

Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma.

Endocrinology and metabolism (Seoul, Korea) - 1 Apr 2021

Jung Hyein, Kim Kyungwon, Kim Daham, Moon Ju Hyung, Kim Eui Hyun, Kim Se Hoon, Ku Cheol Ryong, Lee Eun Jig

Abstract excerpt

BACKGROUND: The guanine nucleotide-binding protein, alpha stimulating (GNAS) gene has been associated with growth hormone (GH)-secreting pituitary adenoma. We investigated the prevalence of GNAS mutations in Korean patients with acromegaly and assessed whether mutation status correlated with biochemical or clinical characteristics. METHODS: We studied 126 patients with acromegaly who underwent surgery between...

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Identifiers

PMID: 33752302
DOI: 10.3803/EnM.2020.875
PMCID: PMC8090461

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