Article
The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas.
Clinical endocrinology - 1 Apr 2007
Iwata Takeo, Yamada Shozo, Mizusawa Noriko, Golam Hossain Md, Sano Toshiaki, Yoshimoto Katsuhiko
Abstract excerpt
BACKGROUND: Recently, germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene located on 11q13 were identified in patients with pituitary adenoma predisposition. AIM/PATIENTS AND METHODS: We investigated the involvement of the AIP gene in one family with isolated familial somatotropinomas (IFS). To investigate the role of AIP in sporadic GH-secreting adenomas, we first analysed somatic...
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