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Article

Clinical features and treatment of pediatric somatotropinoma: case study of an aggressive tumor due to a new AIP mutation and extensive literature review.

Hormone research in paediatrics - 1 Jan 2011

Personnier Claire, Cazabat Laure, Bertherat Jérôme, Gaillard Stephan, Souberbielle Jean-Claude, Habrand Jean Louis, Dufour Christelle, Clauser Eric, SainteRose Christian, Polak Michel

Abstract excerpt

CONTEXT: Pediatric somatotropinoma is uncommon but usually more aggressive than in adults, creating therapeutic challenges. No treatment guidelines are available. OBJECTIVES: To describe the features of pediatric somatotropinomas and to assess therapeutic strategies based on an extensive literature review. DESIGN: We describe a pediatric case of aggressive somatotropinoma with an AIP mutation. We identified 137...

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Source

Identifiers

PMID: 21546764
DOI: 10.1159/000327831

Genes

AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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