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Article

Pathogenesis of familial acromegaly.

Frontiers of hormone research - 1 Jan 2010

Gadelha Mônica R, Frohman Lawrence A

Abstract excerpt

Familial acromegaly may occur as a component of syndromes of multiple endocrine neoplasia or as isolated familial somatotropinoma (IFS), which is included in the spectrum of familial isolated pituitary adenoma (FIPA). We review the pathogenesis of IFS, from the detection of loss of heterozygosity at chromosome 11q13 and establishment of linkage to this chromosome region to the description of germline mutations in...

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Source

Identifiers

PMID: 20616502
DOI: 10.1159/000318501

Genes

AIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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