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Article

CCSP G38A polymorphism environment interactions regulate CCSP levels differentially in COPD.

American journal of physiology. Lung cellular and molecular physiology - 1 Oct 2016

Knabe Lucie, Varilh Jessica, Bergougnoux Anne, Gamez Anne-Sophie, Bonini Jennifer, Pommier Alexandra, Petit Aurélie, Molinari Nicolas, Vachier Isabelle, Taulan-Cadars Magali, Bourdin Arnaud

Abstract excerpt

Impaired airway homeostasis in chronic obstructive pulmonary disease (COPD) could be partly related to club cell secretory protein (CCSP) deficiency. We hypothesize that CCSP G38A polymorphism is involved and aim to examine the influence of the CCSP G38A polymorphism on CCSP transcription levels and its regulatory mechanisms. CCSP genotype and CCSP levels in serum and sputum were assessed in 66 subjects with...

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Identifiers

PMID: 27496897
DOI: 10.1152/ajplung.00280.2016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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