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Article

dextro- and levo-morphine attenuate opioid delta and kappa receptor agonist produced analgesia in mu-opioid receptor knockout mice.

European journal of pharmacology - 15 Feb 2006

Wu Hsiang-en, Sun Han-Sen, Terashivili Maia, Schwasinger Emma, Sora Ichiro, Hall F Scott, Uhl George R, Tseng Leon F

Abstract excerpt

We have demonstrated that the antianalgesia induced by dextro-morphine and levo-morphine is not mediated by the stimulation of mu-opioid receptors in male CD-1 mice. We now report that the dextro-morphine and levo-morphine attenuated antinociception produced by delta-opioid receptor agonist deltorphin II and kappa-opioid receptor agonist U50,488H given spinally in the male mu-opioid receptor knockout mice. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16445907
DOI: 10.1016/j.ejphar.2005.12.012

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