Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition

5 Aug 2016

Abstract excerpt

Epigenome-wide association studies of prenatal exposure to different environmental factors are becoming increasingly common. These studies are usually performed in umbilical cord blood. Since blood comprises multiple cell types with specific DNA methylation patterns, confounding caused by cellular heterogeneity is a major concern. This can be adjusted for using reference data consisting of DNA methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Neonatal Respiratory Health Research
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27494297
DOI: 10.1080/15592294.2016.1214782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type compositionPMID 27494297Read ↗

Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord bloodSemantic proximity Read ↗

Cell type-specific DNA methylation in neonatal cord tissue and cord blood: a 850K-reference panel and comparison of cell typesSemantic proximity Read ↗

DNA methylation of cord blood cell types: Applications for mixed cell birth studiesSemantic proximity Read ↗

Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studiesSemantic proximity Read ↗

Reference-Based Versus Reference-Free Cell Type Estimation In DNA Methylation Studies Using Human Placental TissueSemantic proximity Read ↗

DNA Methylation Patterns in Cord Blood of Neonates Across Gestational AgeSemantic proximity Read ↗

Estimation of blood cellular heterogeneity in newborns and children for epigenome‐wide association studiesSemantic proximity Read ↗

Accurate prediction of cell composition, age, smoking consumption and infection serostatus based on blood DNA methylation profilesSemantic proximity Read ↗

Cell-type deconvolution in epigenome-wide association studies: a review and recommendations.Semantic proximity Read ↗

Leveraging epigenetic signatures to determine the cell-type of origin from long read sequencing dataSemantic proximity Read ↗

Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cellsSemantic proximity Read ↗

Accounting for cellular heterogeneity is critical in epigenome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.