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DNA methylation of cord blood cell types: Applications for mixed cell birth studies

28 Mar 2016

Abstract excerpt

Epigenome-wide association studies of disease widely use DNA methylation measured in blood as a surrogate tissue. Cell proportions can vary between people and confound associations of exposure or outcome. An adequate reference panel for estimating cell proportions from adult whole blood for DNA methylation studies is available, but an analogous cord blood cell reference panel is not yet available. Cord blood has...

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PMID: 27019159
DOI: 10.1080/15592294.2016.1161875

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