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Article

Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril

4 Aug 2016

Abstract excerpt

A single amyloidogenic protein is implicated in multiple neurological diseases and capable of generating a number of aggregate "strains" with distinct structures. Among the amyloidogenic proteins, α-synuclein generates multiple patterns of proteinopathies in a group of diseases, such as Parkinson disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). However, the link between specific...

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PMID: 27488222
DOI: 10.1038/srep30891

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