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Article

Structure of the human DNA-repair protein RAD52 containing surface mutations.

Acta crystallographica. Section F, Structural biology communications - 1 Aug 2016

Saotome Mika, Saito Kengo, Onodera Keiichi, Kurumizaka Hitoshi, Kagawa Wataru

Abstract excerpt

The Rad52 protein is a eukaryotic single-strand DNA-annealing protein that is involved in the homologous recombinational repair of DNA double-strand breaks. The isolated N-terminal half of the human RAD52 protein (RAD52(1-212)) forms an undecameric ring structure with a surface that is mostly positively charged. In the present study, it was found that RAD52(1-212) containing alanine mutations of the charged...

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Source

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Identifiers

PMID: 27487923
DOI: 10.1107/S2053230X1601027X
PMCID: PMC4973300

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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