Article
Genomic characterization of response to chemoradiation in urothelial bladder cancer.
Cancer - 1 Dec 2016
Desai Neil B, Scott Sasinya N, Zabor Emily C, Cha Eugene K, Hreiki Joseph, Sfakianos John P, Ramirez Ricardo, Bagrodia Aditya, Rosenberg Jonathan E, Bajorin Dean F, Berger Michael F, Bochner Bernard H, Zelefsky Michael J, Kollmeier Marisa A, Ostrovnaya Irina, Al-Ahmadie Hikmat A, Solit David B, Iyer Gopa
Abstract excerpt
BACKGROUND: The authors characterized the genetic landscape of chemoradiation-treated urothelial carcinoma of the bladder (UCB) with the objective of identifying potential correlates of response. METHODS: Primary tumors with (n = 8) or without (n = 40) matched recurrent tumors from 48 patients who had non-metastatic, high-grade UCB and received treatment primarily with chemoradiation were analyzed using a...
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