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Article

Mutational pattern off homologous recombination repair (HRR)-related genes in upper tract urothelial carcinoma.

Cancer medicine - 1 Jul 2023

Yang Kaiwei, Yu Wei, Liu Huanhuan, Lou Feng, Cao Shanbo, Wang Huina, He Zhisong

Abstract excerpt

BACKGROUND: Homologous recombination (HR) repair (HRR) has been indicated to be a biomarker for immunotherapy, chemotherapy, and poly-ADP ribose polymerase inhibitors inhibitors (PARPis). Nonetheless, their molecular correlates in upper tract urothelial carcinoma (UTUC) have not been well studied. This study aimed to explore the molecular mechanism and tumor immune profile of HRR genes and the relevance of their...

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Identifiers

PMID: 37387466
DOI: 10.1002/cam4.6175
PMCID: PMC10417099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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