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Article

Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets.

European urology - 1 Dec 2017

Pietzak Eugene J, Bagrodia Aditya, Cha Eugene K, Drill Esther N, Iyer Gopa, Isharwal Sumit, Ostrovnaya Irina, Baez Priscilla, Li Qiang, Berger Michael F, Zehir Ahmet, Schultz Nikolaus, Rosenberg Jonathan E, Bajorin Dean F, Dalbagni Guido, Al-Ahmadie Hikmat, Solit David B, Bochner Bernard H

Abstract excerpt

BACKGROUND: Molecular characterization of nonmuscle invasive bladder cancer (NMIBC) may provide a biologic rationale for treatment response and novel therapeutic strategies. OBJECTIVE: To identify genetic alterations with potential clinical implications in NMIBC. DESIGN, SETTING, AND PARTICIPANTS: Pretreatment index tumors and matched germline DNA from 105 patients with NMIBC on a prospective Institutional Review...

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Source

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Identifiers

PMID: 28583311
DOI: 10.1016/j.eururo.2017.05.032
PMCID: PMC6007852

Genes

ERBB2
FGFR3
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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