Article
Histamine prevents radiation-induced mesenchymal changes in breast cancer cells.
Pharmacological research - 1 Sept 2016
Galarza Tamara E, Mohamad Nora A, Táquez Delgado Mónica A, Vedoya Guadalupe M, Crescenti Ernesto J, Bergoc Rosa M, Martín Gabriela A, Cricco Graciela P
Abstract excerpt
Radiotherapy is a prime option for treatment of solid tumors including breast cancer though side effects are usually present. Experimental evidence shows an increase in invasiveness of several neoplastic cell types through conventional tumor irradiation. The induction of epithelial to mesenchymal transition is proposed as an underlying cause of metastasis triggered by gamma irradiation. Experiments were conducted...
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