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Article

Inhibition of Notch signaling pathway enhanced the radiosensitivity of breast cancer cells.

Journal of cellular biochemistry - 1 Nov 2018

Peng Jian-Heng, Wang Xiao-Lin, Ran Liang, Song Jun-Long, Zhang Zhi-Ting, Liu Xin, Li Hong-Yuan

Abstract excerpt

This study aimed to investigate the effect of inhibiting the Notch signaling pathway on the radiosensitivity of breast cancer cells. Human breast cancer cell lines (MCF-7 and T47D) were selected and treated with radiation of different doses. Cells were treated with Gamma secretase inhibitor (GSI) to analyze the effects of GSI on the Notch signaling, which were detected by Immunofluorescence assay, RT-qPCR, and...

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Source

Identifiers

PMID: 29904942
DOI: 10.1002/jcb.27036

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RBPJ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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