Article
Early Impairment of Paracrine and Phenotypic Features in Resident Cardiac Mesenchymal Stromal Cells after Thoracic Radiotherapy.
International journal of molecular sciences - 1 Mar 2024
Picchio Vittorio, Gaetani Roberto, Pagano Francesca, Derevyanchuk Yuriy, Pagliarosi Olivia, Floris Erica, Cozzolino Claudia, Bernava Giacomo, Bordin Antonella, Rocha Filipe, Pereira Ana Rita Simões, Ministro Augusto, Pinto Ana Teresa, De Falco Elena, Serino Gianpaolo, Massai Diana, Tamarat Radia, Pesce Maurizio, Santos Susana Constantino Rosa, Messina Elisa, Chimenti Isotta
Abstract excerpt
Radiotherapy-induced cardiac toxicity and consequent diseases still represent potential severe late complications for many cancer survivors who undergo therapeutic thoracic irradiation. We aimed to assess the phenotypic and paracrine features of resident cardiac mesenchymal stromal cells (CMSCs) at early follow-up after the end of thoracic irradiation of the heart as an early sign and/or mechanism of cardiac...
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