[Association between interleukin-18 gene polymorphisms and hepatocellular carcinoma caused by hepatitis B virus].

doi:10.3760/cma.j.issn.1007-3418.2016.05.008

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

[Association between interleukin-18 gene polymorphisms and hepatocellular carcinoma caused by hepatitis B virus].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 20 May 2016

Zhang Q X, Yao Y Q, Li S L, Long Q

Abstract excerpt

OBJECTIVE: To investigate the association between the single nucleotide polymorphisms (SNPs) IL-18-137G/C (rs187238) and IL-18-607A/C (rs1946518) in interleukin-18 (IL-18) gene and hepatocellular carcinoma (HCC) caused by the hepatitis B virus (HBV). METHODS: The subjects were divided into HBV-related HCC group (109 patients), chronic HBV infection group (113 patients), and healthy control group (127 patients)....

Topics

Alleles
Carcinoma, Hepatocellular
Case-Control Studies
Gene Frequency
Genotype
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B, Chronic

Humans

Interleukin-18

Liver Neoplasms

Odds Ratio

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27470888
DOI: 10.3760/cma.j.issn.1007-3418.2016.05.008
PMCID: PMC12769519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27470888-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Association between interleukin-18 gene polymorphisms and hepatocellular carcinoma caused by hepatitis B virus].PMID 27470888Read ↗

Association between Interleukin-18 Polymorphisms and Hepatocellular Carcinoma Occurrence and Clinical Progression.Semantic proximity Read ↗

Association of polymorphisms of interleukin-18 gene promoter region with chronic hepatitis B in Chinese Han population.Semantic proximity Read ↗

Association of Interleukin-18 genotypes (-607 C>A ) and (-137 G>C) with the hepatitis B virus disease progression to hepatocellular carcinomaSemantic proximity Read ↗

Association of interleukin-18 genotypes (-607C > A) and (-137 G > C) with the hepatitis B virus disease progression to hepatocellular carcinoma.Semantic proximity Read ↗

[Relationship of interleukin-18 gene promoter polymorphisms with chronic hepatitis B in Chinese Han population].Semantic proximity Read ↗

Role of IL-18 Gene Promoter Polymorphisms, Serum IL-18 Levels, and Risk of Hepatitis B Virus-related Liver Disease in the Guangxi Zhuang Population: a Retrospective Case-Control Study.Semantic proximity Read ↗

Association of genetic variants in the interleukin-18 gene promoter with risk of hepatocellular carcinoma and metastasis in patients with hepatitis C virus infection.Semantic proximity Read ↗

Association of interleukin-18 gene polymorphism (-607A/A genotype) with susceptibility to chronic hepatitis B virus infection.Semantic proximity Read ↗

IL-17 Genetic Variations Increase The Risk of Cirrhotic/Hepatocellular Carcinoma in Patients with Hepatitis B Virus Infection.Semantic proximity Read ↗

Genetic polymorphisms -137 (rs187238) and -607 (rs1946518) in the interleukin-18 promoter may not be associated with development of hepatocellular carcinoma.Semantic proximity Read ↗

IL-18 variant increases risk of enhanced HBV DNA replication in chronic hepatitis.Semantic proximity Read ↗

Interleukin-12B+1188A/C polymorphism contributes to increased hepatocellular carcinoma susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.