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Article

IL-17 Genetic Variations Increase The Risk of Cirrhotic/Hepatocellular Carcinoma in Patients with Hepatitis B Virus Infection.

Iranian journal of immunology : IJI - 1 Jun 2021

Gheshlaghi Abolfazl, Haghshenas Mohammad Reza, Safarpour Ali Reza, Hosseini Seyed Younes, Fattahi Mohammad Reza, Sarvari Jamal

Abstract excerpt

BACKGROUND: Genetic variation in immune regulatory genes might influence the HBV infection outcome. OBJECTIVE: This study aimed to determine the association of IL-17A rs2275913 (G197A), IL-17F rs763780 (A7488G), and IL-23R rs10889677 (C2370A) gene polymorphisms, as well as the emerged haplotypes in the individual infected by HBV and to investigate their association with the infection outcome. MATERIALS AND...

Topics

Adult
Carcinoma, Hepatocellular
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Haplotypes

Hepatitis B

Humans

Interleukin-17

Liver Cirrhosis

Liver Neoplasms

Male

Middle Aged

Polymorphism, Single Nucleotide

Receptors, Interleukin

Risk

Young Adult

Source

Identifiers

PMID: 34190694
DOI: 10.22034/iji.2021.88020.1852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34190694-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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