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Article

IL-18 variant increases risk of enhanced HBV DNA replication in chronic hepatitis.

Immunology letters - 1 Dec 2020

Ben Selma Walid, Alibi Sana, Smach Mohamed Ali, Saad Afef, Boukadida Jalel

Abstract excerpt

BACKGROUND: The outcome ofhepatitis B (HBV) infection is influenced by immune responses and host genetics. Interleukin-18 (IL-18) is a determinant factor in controlling the balance of Th1/Th2 during antiviral response.Weexamine therole of two functional polymorphisms -607A/C and-137A/C inIL-18 gene with risk of chronic HBV infection. METHODS AND RESULTS: Genomic DNA isolates were obtained from 200 seropositive...

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Source

Identifiers

PMID: 33038386
DOI: 10.1016/j.imlet.2020.10.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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