Article
Association between Interleukin-18 Polymorphisms and Hepatocellular Carcinoma Occurrence and Clinical Progression.
International journal of medical sciences - 1 Jan 2016
Lau Hon-Kit, Hsieh Ming-Ju, Yang Shun-Fa, Wang Hsiang-Ling, Kuo Wu-Hsien, Lee Hsiang-Lin, Yeh Chao-Bin
Abstract excerpt
We investigated the association between interleukin-18 (IL-18) polymorphisms and the susceptibility and clinicopathological state of hepatocellular carcinoma (HCC). In total, 901 participants, including 559 healthy controls and 342 patients with HCC, were recruited. The allelic discrimination of -607A/C (rs1946518) and -137G/C (rs187238) polymorphisms of IL-18 was assessed through real-time polymerase chain...
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