Article
Association of interleukin-18 gene polymorphism (-607A/A genotype) with susceptibility to chronic hepatitis B virus infection.
Tissue antigens - 1 Aug 2007
Hirankarn N, Manonom C, Tangkijvanich P, Poovorawan Y
Abstract excerpt
Polymorphisms in the gene promoter can lead to different levels of cytokine expression and let some individuals have unique immune responses. Therefore, the association of single nucleotide polymorphism of interleukin (IL)-18 promoter region in chronic hepatitis B virus (HBV) infection was examined. The results demonstrated the significant involvement of genotype A/A at position -607 in patients (n = 140) when...
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