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Structure and dynamics of H. pylori 98-10 C5-cytosine specific DNA methyltransferase in complex with S-adenosyl-l-methionine and DNA.

Molecular bioSystems - 20 Oct 2016

Singh Swati, Tanneeru Karunakar, Guruprasad Lalitha

Abstract excerpt

Helicobacter pylori is a Gram-negative bacterium that inhabits the human gastrointestinal tract, and some strains of this bacterium cause gastric ulcers and cancer. DNA methyltransferases (MTases) are promising drug targets for the treatment of cancer and other diseases that are also caused by epigenetic alternations of the genome. The C5-cytosine specific DNA methyltransferase from H. pylori (M. Hpy C5mC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27470658
DOI: 10.1039/c6mb00306k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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