Article
The complex methylome of the human gastric pathogen Helicobacter pylori.
Nucleic acids research - 1 Feb 2014
Krebes Juliane, Morgan Richard D, Bunk Boyke, Spröer Cathrin, Luong Khai, Parusel Raphael, Anton Brian P, König Christoph, Josenhans Christine, Overmann Jörg, Roberts Richard J, Korlach Jonas, Suerbaum Sebastian
Abstract excerpt
The genome of Helicobacter pylori is remarkable for its large number of restriction-modification (R-M) systems, and strain-specific diversity in R-M systems has been suggested to limit natural transformation, the major driving force of genetic diversification in H. pylori. We have determined the comprehensive methylomes of two H. pylori strains at single base resolution, using Single Molecule Real-Time (SMRT®)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
