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Article

Recognition of methylated DNA through methyl-CpG binding domain proteins.

Nucleic acids research - 1 Mar 2012

Zou Xueqing, Ma Wen, Solov'yov Ilia A, Chipot Christophe, Schulten Klaus

Abstract excerpt

DNA methylation is a key regulatory control route in epigenetics, involving gene silencing and chromosome inactivation. It has been recognized that methyl-CpG binding domain (MBD) proteins play an important role in interpreting the genetic information encoded by methylated DNA (mDNA). Although the function of MBD proteins has attracted considerable attention and is well characterized, the mechanism underlying...

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Identifiers

PMID: 22110028
DOI: 10.1093/nar/gkr1057
PMCID: PMC3315304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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