Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Movement of DNA sequence recognition domains between non-orthologous proteins.

Nucleic acids research - 1 Oct 2012

Furuta Yoshikazu, Kobayashi Ichizo

Abstract excerpt

Comparisons of proteins show that they evolve through the movement of domains. However, in many cases, the underlying mechanisms remain unclear. Here, we observed the movements of DNA recognition domains between non-orthologous proteins within a prokaryote genome. Restriction-modification (RM) systems, consisting of a sequence-specific DNA methyltransferase and a restriction enzyme, contribute to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Modification Methylases
Share to DNA Restriction-Modification Enzymes
Share to Genetic Loci

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Helicobacter

Share to Helicobacter pylori

Share to Homologous Recombination

Share to Protein Interaction Domains and Motifs

Source

Open in PubMed Open full text

Identifiers

PMID: 22821560
DOI: 10.1093/nar/gks681
PMCID: PMC3467074

Genes

TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Movement of DNA sequence recognition domains between non-orthologous proteins.PMID 22821560Read ↗

Methylome Diversification through Changes in DNA Methyltransferase Sequence SpecificitySemantic proximity Read ↗

Domain Movement within a Gene: A Novel Evolutionary Mechanism for Protein DiversificationSemantic proximity Read ↗

Genome comparison and context analysis reveals putative mobile forms of restriction-modification systems and related rearrangements.Semantic proximity Read ↗

Population Evolution of Helicobacter pylori through Diversification in DNA Methylation and Interstrain Sequence Homogenization.Semantic proximity Read ↗

The Helicobacter pylori HpyAXII restriction–modification system limits exogenous DNA uptake by targeting GTAC sites but shows asymmetric conservation of the DNA methyltransferase and restriction endonuclease componentsSemantic proximity Read ↗

The complex methylome of the human gastric pathogen Helicobacter pylori.Semantic proximity Read ↗

Evolved to vary: genome and epigenome variation in the human pathogen Helicobacter pylori.Semantic proximity Read ↗

Comparative genomics of the restriction-modification systems in <i>Helicobacter pylori</i>Semantic proximity Read ↗

Epigenetic regulation in prokaryotes: transcriptional and phenotypic outcomes of DNA methyltransferase activity.Semantic proximity Read ↗

Mutations in hpyAVIBM, C⁵ cytosine DNA methyltransferase from Helicobacter pylori result in relaxed specificity.Semantic proximity Read ↗

Insertion with long target duplication: a mechanism for gene mobility suggested from comparison of two related bacterial genomes.Semantic proximity Read ↗

Impacts of <i>Mycoplasma agalactiae</i> restriction-modification systems on pan-epigenome dynamics and genome plasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.