Article
Movement of DNA sequence recognition domains between non-orthologous proteins.
Nucleic acids research - 1 Oct 2012
Furuta Yoshikazu, Kobayashi Ichizo
Abstract excerpt
Comparisons of proteins show that they evolve through the movement of domains. However, in many cases, the underlying mechanisms remain unclear. Here, we observed the movements of DNA recognition domains between non-orthologous proteins within a prokaryote genome. Restriction-modification (RM) systems, consisting of a sequence-specific DNA methyltransferase and a restriction enzyme, contribute to...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- DNA Modification Methylases
- DNA Restriction-Modification Enzymes
- DNA-Binding Proteins
- Evolution, Molecular
- Genes, Bacterial
- Genetic Loci
- Genetic Variation
- Genome, Bacterial
- Helicobacter
- Helicobacter pylori
- Homologous Recombination
- Molecular Sequence Data
- Phylogeny
- Protein Interaction Domains and Motifs
- Sequence Alignment
- Treponema denticola