Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of Phosphatase and tensin homolog (PTEN) deletion and prostate cancer risk: A meta-analysis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2016

Gao Tianyi, Mei Yanping, Sun Huiling, Nie Zhenlin, Liu Xiangxiang, Wang Shukui

Abstract excerpt

OBJECTIVE: Phosphatase and tensin homolog (PTEN) deleted on chromosome 10, a tumor suppressor that negatively regulates the phosphoinositide-3-kinase(PI3K) which has been implicated in a number of human malignancies including prostate cancer. However the prognostic value of PTEN deletion in prostate cancer patient's diagnosis and the mechanism of PTEN deletion in prostate cancer development still remain unclear....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Deletion
Share to ERG gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Genetic Predisposition to Disease

Share to Prostatic Neoplasms

Share to PTEN Phosphohydrolase

Share to Publication Bias

Share to Risk Factors

Source

Identifiers

PMID: 27470558
DOI: 10.1016/j.biopha.2016.06.020

Genes

PTEN
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of Phosphatase and tensin homolog (PTEN) deletion and prostate cancer risk: A meta-analysis.PMID 27470558Read ↗

Clinical Utility and Biologic Implications of Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) in Prostate Cancer.Semantic proximity Read ↗

The PTEN Conundrum: How to Target PTEN-Deficient Prostate CancerSemantic proximity Read ↗

Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis.Semantic proximity Read ↗

Genomic Rearrangements of PTEN in Prostate CancerSemantic proximity Read ↗

PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohortSemantic proximity Read ↗

Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?Semantic proximity Read ↗

Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer.Semantic proximity Read ↗

Clinical implications of PTEN loss in prostate cancer.Semantic proximity Read ↗

PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profilesSemantic proximity Read ↗

Role of PTEN gene in progression of prostate cancer.Semantic proximity Read ↗

ERG Rearrangement Is Associated with Prostate Cancer-Related Death in Chinese Prostate Cancer PatientsSemantic proximity Read ↗

Prostate cancer, PI3K, PTEN and prognosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.