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Article

Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis.

BMC medical genetics - 2 Dec 2019

Sun Jian, Li Shugen, Wang Fei, Fan Caibin, Wang Jianqing

Abstract excerpt

BACKGROUND: Prostate cancer (Pca) remains one of the leading adult malignancies. PTEN (Phosphatase and Tensin Homolog) mutant is the top common mutated genes in prostate cancer, which makes it a promising biomarker in future individualized treatment. METHODS: We obtained gene expression data of prostate cancer from TCGA (The Cancer Genome Atlas) database for analysis. We analyzed the DEGs (differentially...

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Identifiers

PMID: 31791268
DOI: 10.1186/s12881-019-0923-7
PMCID: PMC6889628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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